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Resveratrol activeaza Sirtuina care creste functia mitocondriala, creste rata metabolica si mimeaza efectul de restrictie calorica
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Resveratrol activeaza gena care promoveaza Longevitatea
Terapia Anti-Aging cu
Carnosina |
Carnosina cu actiune de longevitate (Life Extension) |
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14. Carnosina ca enigma sa exemplificat prin actiunea Anti-Aging un antioxidan anti glicozilare, cu abilitate de influenta in metabolismul alterat al polipeptizilor cu reparatia proteinelor alterate, participa in reparatia grupa aspartil a proteinelor, cu proprietati de chelare a ionilor toxici a metalelor, anti-convulsant, un inhibitor la senescenta fibroblastelor un inhibitor de fosforilare in initierea translatiei factorului eIF4E, in mutatii la nivelul genei eIF4E care influentea prelungirea vietii - Longevitate
15. L-Carnozina cu efect de reintinerire (rejuvenating effects) in cultura umana de fibroblast - Celula a tesutului conjunctiv nediferentiata
Fibroblast este celula a tesutului conjunctiv nediferentiata
16. Carnosina cu efect de intirziere a senescentei in cultura umana de fibroblast
| Fibroblast uman normal | Fibroblast cu morfologie de senescenta declin cognitiv |
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 |
17. L-Carnosina reduce dauna de telomere cu rata de scurtare a telomerelor in cultura de fibroblast
| Carnosina reduce rata de scurtare telomerelor: Telomer (Telomere) se scurteza cu diviziunea celulara | Cromozom cu secvente de telomer la capat |
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Carnosina creste rata de Telomer (Telomere) cu fragmente scurtate (-)
18. Reactia Maillard cu formarea de glicozilare avansata AGEs in vivo
19. Mecanism de actiune a formarii reactiei Maillard cu pentozidina proteina incrucisata
20
Reactia Maillard la boala de diabet zaharat si imbatranire
21
Carnosina Anti-Aging antioxidant dipeptid reactioneaza cu monoxidul de carbon
(grupa de carbonil) a proteinelor rectie numita carbonilarea proteinelor
22. L-Carnozina reactioneaza cu grupa de carbonil a proteinelor aceasta reactie se numeste reactie de carnozilare (carnosinylated' protein), un alt posibil rol a dipeptidului Anti-Aging
23. Carbonilarea proteinelor in bolile umane
24. Reactia de Carbonilare modifica proteinele in reglarea celulara, a imbatranirii si a bolilor
25
Carnosina
si grupa de carbonil a proteinei o posibila relatie Anti-Ageing
26. Produsi realizati in reactia Maillard: Schiff base, Aminodori, Age, Pentozidina, Carboximetil lizina (CML)
27. Carnosina cu actiune de chelare a produsilor realizati in reactia Maillard: Schiff base, Aminodori, Age, Pentozidina, Carboximetil lizina (CML)
28. Ceai Verde cu flavonoizi atenueaza la diabet reactia Maillard si reactia de incrucisare (Cross-linking) a colagenului la inima pacientilor cu diabet
29. Flavonoizii sint polifenoli inhiba formarea de rectii de incrucisare AGEs de glicare a pentozidinei cu incubarea de glucoza
30. Oxidarea proteinei glicozilate in cristalin lentila si cresterea acumularii de Carboximetil lizina (CML) cu varsta
31. Acumularea dependent de varsta a Carboximetil lizina (CML) si carboximetil hidroxil lizina in pielea colagenului uman
32. Efectul diabetului in imbatranire si nivelul de Carboximetil lizina (CML) in urina
33. Formarea de Pentozidina in timpul reactiei non enzimatice de brunare a proteinelor indusa de glucoza si alti carbohidrati precursori de pentozidina in vivo
 Carnosina
reda eslasticitatea tesutului de colagen indusa de reactiile de glicozilare
prin brunare |
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34. Imbatranirea colagenului in vitro prin reactia de glicozilare si de brunare
35. Chimia ne enzimatica de brunare
36. Elucidarea structurii senescentei de incrucisare al matrixului extra celular uman si implicatia de Pentoza in procesul de imbatranire
37. Albumina glicozilata stresul oxidativ la diabet zaharat si imbatranirea
Biomarkeri celulari ai imbatranirii sint: Pentozidina, Carboximetil lizina (CML), Albumina glicozilata, Hemoglobina glicozilata (HbA1c), Age hemoglobina modificata (Hb-AGE)
Secretul Longevitatii: Mentinerea de Hemoglobina glicozilata - (HbA1c) la valoarea de 5%, valoare
optimala este reducerea glucozei la nivelul de 70 - 80 mg/dl
Dar pentru managementul zilnic cu Self-monitoring Blood Glucose Profile (SMBG)
pentru ajustarea terapiei respectiv de Hemoglobina glicozilata - hemoglobina
A1c la 5% - 70 - 80 mg/dl valoarea optimala
Masurarea
de Hemoglobina glicozilata - hemoglobina A1c nu este limitata fata de
variabilitatii glicemice
Hemoglobina
A1c nu diferentiaza glicemia de fasting - post, prandiala, si postprandiala
38. Glicozilarea ne enzimatica a colagenului in piele la pacienti diabet tip I insulino dependenti si cu limitarea mobilitatii articulare
39. Glicozilarea a colagenului in piele la diabet tip I
40
Taurina previne anormalitatea de colagen indusa de hrana bogata cu fructoza
41 Taurina previne
anormalitatea de colagen in piele indusa de fructoza
42. Administrarea de Taurina influenteaza pozitiv la anormalitatea de colagen in piele, indusa de hrana bogata cu fructoza
43. Accelerarea imbatranirii colagenului uman la diabet zaharat
44. Stadiul final bolile renale si catalizarea de diabet la formarea derivatilor de pentoza incrucisata cu colagenul uman
45. Procesul de glico-oxidare si imbatranirea, prin expunerea la hrana care favorizeaza glicozilarea ( exposure to dietary AGE (dAGEs)
46. Prin expunerea la glicotoxine reduse si cresterea expresiei de AGER1 cu capacitate antioxidanta de reducerea stresului oxidativ de radicalii liberi se prelungeste viata (extended lifespan)
47. Reactiile de glicozilare avansata AGEs se leaga de moleculele
receptorilor AGE (Receptors for AGE, RAGE), este involvata in imbatranire
si la bolile neurodegenerative
48. Glicarea avansata AGEs si RAGE cu rol patologic, involvat in bolile de
ficat
49
Acid Alfa Lipoic previne anormalitatea colagenului pielii indusa de fructoza
50 Acid Alfa Lipoic previne anormalitatea colagenului
tip I din tendon indusa de hrana bogata in fructoza
51. Ceai Verde cu efect la glicarea avansata AGEs si la reactia de incrucisare colagenului tip I din aorta si tendon la diabet
52. Ceai Verde impiedica peroxidarea lipidica si dislipidemia, glicarea proteinelor la diabetici
53
Chlorella alga unicelulara potential terapeutic in glicarea avansata AGEs
cu efect anti aterogenic in ateroscleroza
54. Modificarea - Aminodori a proteinei glicate accelereaza ateroscleroza in diabet, implicatii terapeutice si patogenice
Glicarea colagenului in patogeneza arteriala si rigidizarea vaselor de singe care iriga inima
Procesul de ateroscleroza cu leziunile de aterom si scleroza |
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Procesul aterosclerotic: Cauze, simptome, tratament si profilaxie
Cauze organice: Din lipsa cronica de Vitamina C in peretii vasculari se formareaza leziuni iar efectele de reparatie a organizmului
compenseaza necontrolat cresterea cu celule musculare si depuneri de
Lipoproteina(a) = apoa in
placa aterosclerotica.
Evidenta acumularii Lipoproteinei (apoa) in leziunea aterosclerotica:
- Liproproteina(apoa) are efect de lipire (Adeziune) de peretii vasculari, nivelul seric crescut de colesterol total, depunerile moleculelor de Calciu si molecule de zahar (glucoza), participa si ele in ingrosarea prin depuneri in peretele arterial
- Stenoza este ingustarea lumenului arterial care poate surveni prin fisurarea ingrosarii, cu depuneri de trombi (cheaguri de sange), vasele de sange se astupa si intrerupe fluxul sanguin prin formarea de cheaguri (tromboza).
- Simptome: Prezenta aterosclerozei se observa la efort cind nevoia de oxigen a musculaturii este mai mare iar fluxul de sange scazut.
Tratament:
Vasodilatori L-Arginina datorita rigidizarii vaselor de sange, fluiditatea singelui Ulei de Peste, Vitamina E,
- Profilaxie: Terapia prin Chelare a calciului, fierului, aluminiului sau metale grele, apoi mentinerea unui status de sanatate Anti-Aging - Longevitate
55
Anti-Aging News: Importanta terapeutica de chelare a fierului: Inhibarea absorbtiei de Fier prelungeste viata - Longevitate ( prolongs the
life span)
56 Evidenta teoriei de incrucisare (crosslinking) - Supraincarcarea cu aluminiu
induce reactii de incrucisare
57
Extract din Samburi de Struguri cu procianidine are efect anti hiperglicemic
si mimeaza insulina (insulinomimetic) in celulele senzitive de insulina
58. Extract din Samburi de Struguri cu procianidine cu flavonoizi este
mul mai activ in inhibarea de glicare in preventia si complicatiile la
diabet, ca pin maritim francez (pinus maritima) Pygnogenol
cu oligomeri sai
59. Extract din Samburi de Struguri cu procianidine si comparatia antioxidanta fata de pin maritim francez (pinus maritima) Pygnogenol
60. Extract din Samburi de Struguri cu procianidine induce apoptoza la celulele de leucemie prin activarea de c- jun NH2-terminal kinaza
Extract din Samburi de Struguri
Extract Standardizat 95% OPC
 |
despre: Extract din Samburi de Struguri |
Acetil L-Carnitina cu efect Anti Aging
61
Acetil L-Carnitina un Star poate suplimentar trece bariera hepatoencefalica,
este involvat ca mijloc de transport de L-Carnitina si poate restaura nivelul scazut de L-Carnitina in cerebral
62 Acetil L-Carnitina un: Elixir al tineretii - Acetil L-Carnitina (ALC) + Acid Alfa Lipoic (AAL) prin reducerea de stres oxidativ
si a oxidarii ADN/ARN se incetineste procesul de inbatrinire la mitocondria
care este uzina energetica de ATP
Acetil L-Carnitina un: Elixir al tineretii - Acetil L-Carnitina (ALC - ALCAR) si Acid Alfa Lipoic (AAL -
LA) efect Anti-Aging
63 Carnosina de la Anti-Aging-Systeme este o dipeptida Anti-Ageing numita si b-alanil-L-histidina
cu rol de Anti-Ageing Anti-imbatranire: Anti Aging Formula
64
Carnosina de la Anti-Aging-Systeme este un natural aminoacid L-Carnosina cu
protectie Anti-Aging
65 Carnosina de la Anti-Aging-Systeme este un potent natural aminoacid L-Carnosina
cu protectie Anti-Aging
66
Carnosina un miraculos antisenescent, creste
vitalitatea, prelungeste tineretea, intirzie imbatranirea AntiAging
reduce accelerarea senescentei anti-imbatranire
Suplimente nutritionale Anti-Ageing - Carnosina miraculosul leac Anti-Ageing: Carnosina un alt elixir al tineretii de Marios Kyriazis
67 Carnosina cu proprietati fiziologice si potential terapeutic - Medicina Anti-Aging de Marios Kyriazis
68 Carnosina previne atrofia musculara de pina la 50% in bolile sistemului neuromuscular
si cel musculo-scheletal, cantitatea de Carnosina scade in tesutul muscular
cu 63% intre 10-70 de ani
Carnosina previne atrofia musculara, un produs foarte apreciat la sportivi si
bodybuilder
| Mentinerea diametrului muscular | Atrofie musculara |
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69 Concentratia inalta de Carnosina cu efect in tesutul muscular la sprintul
maximal pe ergometru timp de 30 secunde
70 Efectul de Carnosina si zinc chelat in functia musculara
71 Carnosina cu protectie a fibrelor musculare de oboseala
72
Spirulina alga albastra verzui pastreaza mentine, prezerva degenerarea celulelor,
creste vitalitatea, ne mentinem: Longevivi, prelungeste tineretea intirzie
procesul de imbatranire Longevitate Anti-Aging.
Spirulina si Chlorella izvor
de vitalitate prin mentinerea mediului anabolic datorita continutului de:
L-Arginina, L-Glutamina, L-Lizina, care are efect de eliberare naturala
de Hormonul uman de creştere HGH care este recunoscut ca: Fantana
tineretii (Fountain
of Youth Anti-Aging).
Chlorella si Spirulina stimuleaza secretia hormonului de crestere, un activator HGH tot
atit de eficient, la un pret senzational de ieftin fata de alti activatori
HGH
Spirulina pastreaza starea anabolica care este important in mentinerea diametrului
muscular, care scade pina la 40 % in atrofie musculara, daca nu se previne
procesul catabolic prin a creste masa musculara (efect anti-catabolic).
73 Oxidarea proteinelor prin stresul oxidativ al radicalilor
liberi induce imbatranirea
74. Stresul oxidativ de radicalii liberi induc glicozilarea la pacienti cu boala pulmonara obstructiva cronica (COPD)
75. Stresul oxidativ prin radicalii liberi cresc glicozilarea la hemoglobina in disfunctia renala
76. Nivelul de stres oxidativ prin radicalii liberi si glicozilarea proteinelor la non diabetici pacientiilor cu disfunctie renala
77. Evidenta rolului de peroxidarea lipidelor la glicozilarea hemoglobinei si plasma proteinelor la non diabetici pacienti cu astma
78. Baza biochimica de complicatii la diabet prin formarea de AGEs (Advanced glycosylation end products)
79. Reactia de incrucisare ( Cross-linking) de glicare a colagenului in patogeneza arteriala si rigidizarea vaselor de singe care iriga inima la inbatranire si diabet
80. Glicarea proteinelor, diabetul si imbatranirea
81. Reactia ne enzimatica de glucoza cu grupa amino de la proteine formind AGEs este corelat cu fiziologia ambatranirii si diabetul sever
82. Carnosina un modulator intracelular al calciului in contractia celulelor cardiace
83. Carnosina previne ischemia-reperfuzia indusa de dauna renala
84. Reactia ne enzimatica de glicare a proteinelor in singe si la bolile cardiovasculare
85. Cresterea glicozilarii hemoglobinei si proteinele plasmatice este asociata cu cresterea nivelului peroxid la non diabetici
86 Carnosina reduce reactiile de glicozilare (AGEs) de incrucisare (crosslinking) cu glucoza, Carnosine cu efect benefic
reduce oxidarea proteinelor de origine animala
87 Carnosina un inhibitor al cu actiune de anti-glicozilare in hrana proteica,
inhiba imbatranirea si alte patologii
88 Carnosina intirzie procesul de imbatranire, ne mentinem: Longevivi reduce oxidarea proteinelor de origine animala care este un factor de risc pentru
alte patologii
89 Carnosina reduce reactiile de glicozilare (AGEs) de incrucisare (crosslinking)
cu glucoza, Carnosine cu efect benefic reduce oxidarea proteinelor de origine
animala
90 Carnosina reduce degradarea proteica (proteoliza) prin peroxidarea lipidica cauza
degradarii proteice, reduce reactiile de glicozilare (AGEs) de incrucisare
(crosslinking) cu glucoza si cu efect protectiv in rectiile de malonilare
91 Carnosina
un protector proteinelor inhiba Metilglioxal in medierea de modificare
a proteinelor,
Metilglioxal este un metabolit endogen care este prezent
la diabetici, se implica in reactiile de glicozilare (AGEs) si in complicatiile
diabetice
92 Carnosina cu efect in tratamentul dupa accidentul vascular cerebral
93 Carnosina cu efect in tratamentul atac ischemic tranzitor
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despre Carnosina |
Produse Anti-Aging care reduc reactiile de glicozilare (AGEs): Carnosina, Acid Alfa Lipoic, Ceai Verde - EGCG, Extract din Samburi de Struguri - Procianidine, Taurina, Chlorella
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Produsele
favorite ale clientiilor sint produse Anti-Aging cu 5 stele in
top: Anti-Aging-Systeme - Formula AntiAging
Anti-Aging-Systeme
- Terapia Anti-Aging
Bibliografie - Referinte Resveratrol Supreme
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20 Thorpe
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21 Hipkiss
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27 Price
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Literatura:
Dr. Ronald Klatz, MD. Robert Goldman - Stopping the Clock: Dramatic Breakthroughs
in Anti-Aging and Aging Reversal Techniques
Dr. MD. Roy L Waldford - Beyond the 120 Year Diet: How to Double Your Vital
Years
Marios Kyriazis - Carnosine : And Other Elixirs of Youth The Miraculous Anti-Ageing
Supplement
Anti-Aging Medicina de M.D. Marios Kyriazis
Jurnalul Anti-Aging Medicina MICHAEL FOSSEL, M.D., Ph.D.
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