6. Graviola (Annona muricata) cu substantele active in frunze de mono tetra hidro furan acetogenina cu actiune la carcinom pulmonar (A-549) si carcinom de colon (HT-29),

7. Graviola (Annona muricata) cu noul citotoxic mono tetra hidro furan Annonaceous acetogenina din Annona muricata

8. Graviola (Annona muricata) cu activitate antitumorala mono tetra hidro furan acetogenina din Annona muricata

9. Graviola (Annona muricata) cu continutul de bullatacina are efect citostatic la adenocarcinomului mamar

Graviola (Annona muricata) cu continutul de bullatacina are efect citostatic la adenocarcinomului mamar

10. Graviola (Annona muricata) cu continutul de bullatacina un potent efectiv antitumoral inhiba virusul de hepatita B si cancerul hepatic

11. Acetogenina din Graviola (Annona muricata) cu actiune selectiva de inhibare la mitocondria complex I

12. Acetogenina o substanta naturala din Graviola (Annona muricata) un inhibitor puternic la mitocondria, regiunea NADH dehidrogenaza (complex I)

13. Acetogenina din Graviola (Annona muricata) un inhibitor de cresterea celulelor tumorale

14. Graviola (Annona muricata) cu continutul de annonacina activitate citostatica la celulele de cancer

Graviola (Annona muricata) cu annonacina activitate citostatica la celulele de cancer

15. Graviola (Annona muricata) cu activitate antibacteriala

16. Graviola (Annona muricata) cu activitate antivirala are efect la Herpes simplex

17. Graviola (Annona muricata) cu activitate antidepresiva

18. Graviola (Annona muricata) cu efect la stres indus de peroxidarea lipidica

19. Graviola (Annona muricata) cu activitate antiparazit

20. Graviola (Annona muricata) cu activitate de insecticid si anti-malarie

Bibliografie-Referinte: Graviola

Informatii din bibliografia electronica la tema: Nutritie si sanatate

 

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2. Chang FR, Wu YC. Novel cytotoxic annonaceous acetogenins from Annona muricata. Graduate Institute of Natural Products, Kaohsiung Medical University, Kaohsiung 807, Taiwan, Republic of China. J Nat Prod. 2001 Jul;64(7):925-31.
3. Jaramillo MC, Arango GJ, González MC, Robledo SM, Velez ID. Cytotoxicity and antileishmanial activity of Annona muricata pericarp. Facultad de Química Farmacéutica, Universidad de Antioquia, A. A. 1226 Medellín, Colombia. Fitoterapia. 2000 Apr;71(2):183-6.
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5. Wu FE, Gu ZM, Zeng L, Zhao GX, Zhang Y, McLaughlin JL, Sastrodihardjo S. Two new cytotoxic monotetrahydrofuran Annonaceous acetogenins, annomuricins A and B, from the leaves of Annona muricata. Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, USA. J Nat Prod. 1995 Jun;58(6):830-6.
- Wu FE, Zeng L, Gu ZM, Zhao GX, Zhang Y, Schwedler JT, McLaughlin JL, Sastrodihardjo S. New bioactive monotetrahydrofuran Annonaceous acetogenins, annomuricin C and muricatocin C, from the leaves of Annona muricata. Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, Indiana 47907, USA. J Nat Prod. 1995 Jun;58(6):909-15.
6. Zeng L, Wu FE, Oberlies NH, McLaughlin JL, Sastrodihadjo S. Five new monotetrahydrofuran ring acetogenins from the leaves of Annona muricata. Purdue University, School of Pharmacy and Pharmacal Sciences, Department of Medicinal Chemistry and Molecular Pharmacology, West Lafayette, Indiana 47907, USA. J Nat Prod. 1996 Nov;59(11):1035-42.
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- Nicolas, H., et al. “Structure-activity relationships of diverse Annonaceous acetogenins against multidrug resistant human mammary adenocarcinoma (MCF-7/Adr) cells.” J. Med. Chem. 1997; 40(13): 2102-6.
- J.L. McLaughlin and Y.-H. Hui, "Chemotherapeutically Active Acetogenins," (bullatacin and bullatacinone) U.S. Patent No. 5,229,419, issued July 20, 1993.
10. Chih HW, Chiu HF, Tang KS, Chang FR, Wu YC. Bullatacin, a potent antitumor annonaceous acetogenin, inhibits proliferation of human hepatocarcinoma cell line 2.2.15 by apoptosis induction. Fooyin Institute of Technology, Kaohsiung County, Taiwan, ROC. Life Sci. 2001 Aug 3;69(11):1321-31.
11. Gonzalez-Coloma, A., et al. “Selective action of acetogenin mitochondrial complex I inhibitors.” Z. Naturforsch. 2002; 57(11-12): 1028-34.
12. Degli Esposti M., Ghelli A., Ratta M., Cortes D. and Estornell E. (1994), Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors
of mitochondrial NADH dehydroganse (complex I). Dipartimento di Biologia, Università di Bologna, Italy. Biochem J. 1994 July 1; 301(Pt 1): 161–167.
13. Oberlies NH, Jones JL, Corbett TH, Fotopoulos SS, McLaughlin JL. Tumor cell growth inhibition by several Annonaceous acetogenins in an in vitro disk diffusion assay. Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907-1333, USA. Cancer Lett. 1995 Sep 4;96(1):55-62.
14. Yuan, S. S., et al. “Annonacin, a mono-tetrahydrofuran acetogenin, arrests cancer cells at the G1 phase and causes cytotoxicity in a Bax- and caspase-3-related pathway.” Life Sci. 2003 May: 72(25): 2853-61.
15. Takahashi JA, Pereira CR, Pimenta LP, Boaventura MA, Silva LG. Antibacterial activity of eight Brazilian Annonaceae plants. Nat Prod Res. 2006 Jan;20(1):21-6.
16. Padma, P., et al. “Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus.” J. Ethnopharmacol. 1998; 61(1): 81–3.
17. Hasrat JA, De Bruyne T, De Backer JP, Vauquelin G, Vlietinck AJ. Isoquinoline derivatives isolated from the fruit of Annona muricata as 5-HTergic 5-HT1A receptor agonists in rats: unexploited antidepressive (lead) products. Department of Pharmaceutical Sciences, University of Antwerp, Belgium. J Pharm Pharmacol. 1997 Nov;49(11):1145-9.
18. Padma, P., et al. “Effect of alcohol extract of Annona muricata on cold immobilization stress induced tissue lipid peroxidation.” Phytother. Res. 1997; 11(4): 326-327.
- Padma, P., et al. “Effect of Annona muricata and Polyalthia cerasoides on brain neurotransmitters and enzyme monoamine oxidase following cold immobilization stress.” J. Natural Remedies 2001; 1(2): 144–46.
19. Bories C, Loiseau P, Cortes D, Myint SH, Hocquemiller R, Gayral P, Cavé A, Laurens A. Antiparasitic activity of Annona muricata and Annona cherimolia seeds. Laboratoire de Parasitologie, Faculté de Pharmacie, Université Paris-Sud, Châtenay-Malabry, France. Planta Med. 1991 Oct;57(5):434-6.
20. Tattersfield, F., et al. “The insecticidal properties of certain species of Annona and an Indian strain of Mundulea sericea (Supli).” Ann. Appl. Biol. 1940; 27: 262–73.
- Gbeassor, M., et al. In vitro antimalarial activity of six medicinal plants. Phytother. Res. 1990; 4(3): 115–17.

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