Garlic Usturoi
Garlic
Usturoi
Garlic cu Alil sulfid inhiba carcinogeneza
Usturoi
(Allium Sativum) - foto

Principalul constituent al usturoiului:
1 Alicina - Formula
chimica - (S-2-propenil-2-propen-1-sulfinotioat)

Formula moleculara este: C6H10OS2
Greutatea moleculara este: 162,276
2 Alil sulfid
din Garlic, Germaniu Organic si I3C (Indole-3-carbinol) inhiba
carcinogeneza.
Alicina (Alicin) este sintetizata in usturoi printr-o reactie enzimatica a enzimei
alinaza (Allinase) care interfereaza conversia de aliina (Aliin),
in alicina.
Scurt si cuprinzator: Usturoiul prin zdrobire aliina este convertita
in alicina de enzima alinaza, exemplu procesul
de zdrobire a cateilor de usturoi.
Binecunoscutul mujdei de usturoi cu importanta zdrobirii cateilor de usturoi
fara de care alinaza din usturoi nu intra in actiune si astfel
nu rezulta alicina
- Se stie prin prepararea termica la 45° se pierde enzimele benefice, iar la
55° vitaminele.
3 Prin prepararea termica Garlic isi pierde abilitatea supresoare de DMBA in
celule mamare
4 Prin influenta de prepararea termica Garlic isi pierde proprietatiile
anti-cancer
5 Garlic cu efect anti-carinogenic la hepatocarcinogeneza
6 Garlic induce apoptoza la DMBA care induce carcinogeneza bucala
7 S-alilcisteina din Garlic cu activitate citostatica, care activeaza si creste
nivelul la enzima Glutation S transferaza
8 Ajone un produs natural din Garlic cu efect citotoxic
9 Mecanismul cu actiune citotoxica de Dialil sulfid un derivat din Garlic
care este convertit in Diallil sulfon de citocrom P 450
10 Inhibarea de citocrom P 450 de Dialil sulfid un derivat din Garlic
11 Garlic in preventia de cancer, meta analiza la cancerul de stomac si colorectal
12 Extractul de Garlic cu potential supresor efectiv la cancerul colorectal
13 S-alilmercaptocisteina din Garlic cu efect antiproliferativ la cancerul de
colon
14 Dialil disulfid din Garlic induce apoptoza la cancerul de vezica urinara
15 Allil sulfid din Garlic regleaza ciclul celular la celulele de tumora hepatica
16 Alicina inhiba polarizarea, divizarea si migrarea, cu efect direct la microtubuli
17 Ajoene din Garlic inhibă reacţia de prenilare a proteinei si proliferarea celulara
18 Leurda si Usturoi au efecte anti-cancer datorita continutului de derivat de
sulf organic (Ajoene)
Leurda
(Allium Ursinum) - foto - Planta cu saminta
 |
Leurda
(Allium Ursinum) - Taxonomia
Regnul:
Plantae - Planta
Increngatura:
Tracheofitelor - Planta vasculara
Subincrengatura:
Spermatofita - Planta cu saminta
Clasa:
Angiosperme - Monocotiledonate - Embrion
Subclasa:
Liliidae
Ordinea:
Liliales
Familia:
Liliaceae
Genul:
Allium L.
Specia:
Allium Ursinum L. - Leurda
|
- Denumire populara: Leoarda, aliu,
aliu de iunie, ai-ciorasc, ai-de-padure, ai-salbatic, aiuti
, ceapa ursului, usturoi de padure.
- Leurda (Allium Ursinum) o planta
erbacee cu flori albe si miros de usturoi, folosit cu succes
in curele depurative de primavara.
- Leurda (Allium Ursinum) contine: derivati
de sulf organic (Ajoene), alicina, dialil sulfid, enzime - alinaza,
vitamine, minerale, aminoacizi, flavonoizi glicolizi
19 Garlic cu proprietati antimutagenice si anticarcinogenice, antitumorale
20. Ajoene din Garlic un agent anti-leucemic
21 Tratamentul
cu Garlic indicat in hiperlipidemie, control randomizat si meta analiza
22 Garlic la copii cu hipercolesterolemia
23 Garlic cu efect la nivelul seric total de colesterol
24 Garlic si Ulei de Peste reduce nivelul seric lipidic si concentratia de lipoproteina
la barbati cu hipercolesterolemie
25 Garlic reduce nivelul seric lipidic, meta analiza
26 Garlic Usturoi (Allium sativum) cu importanta farmaceutica hipolipidemica
in vitro si vivo
27 Garlic cu efect hipolipidemica la masa grasa
28 S-Alchenilcisteina din Garlic inhiba sinteza colesterolului
29 Garlic cu efect la oxidarea LDL si peroxidarea lipidica la pacienti cu hipertensiune
30 Usturoi si Leurda are efect pozitiv in tratamentul de hipertensiune
prin inhibarea enzimei de conversie a angiotensinei (ACE), produce
vasodilatatia si reduce presiunea sanguina prin continutul de gama
glutamil transpeptidaza.
31 Garlic cu efect la nivelul seric lipidic, la formarea placii aterosclerotice
32 Garlic Usturoi
(Allium sativum) cu efect antiaterosclerotic
33 Garlic cu efect la parametri antioxidative la pacientii cu ateroscleroza
34 Garlic moduleaza factorul de risc cardiovascular
35 Garlic, N-Acetilcisteina, inhiba calcificarea coronariana, studiu
36 Leurda cu efect de protectie in ischemia miocardica
37 Garlic
cu Ajoene inhiba agregarea plachetara
38 Dialil
sulfid din Garlic cu efect de protectie de oxidarea si agregarea plachetara
39 Garlic cu efect imunomodulator
40 Garlic cu efect imunomodulator si
antiinflamator
41 Alicina cu ez terapeutic la bolile cu inflamatie
cronica
42 Garlic previne raceala, studiu randomizat dublu orb placebo controlat
43 Alil
tiosulfinat
din Garlic un bateriostatic
la infectia cu Helicobater pilori
44 Principalii constituenti din Garlic dialil sulfid indicat in terapia
helicobacter pilori
45 Garlic cu efctivitate la helicobacter pilori, studiu pilot
46 Garlic are efect antioxidant reduce radicalii liberi
Miracolul antioxidant

Procesul
de imbatranire cu cauzele endogene si exogene
47 Teoria radicalilor liberi in procesul de imbatrinire
-
Radicalii liberi considerati ca mediatori patologici.
-
Formarea de radicali liberi prin: Factorii exogeni ca poluarea
aerului, razele-UV, radiatii ionizante, etc., factorii
endogeni pot fi stres, exercitiu fizic extenuant, inflamatii,
fumat, etc.
-
Tipuri de radicali liberi: Radicalii liberi ai oxigenului,
Radicalii liberi ai azotului, Radicalul thiil,etc
| Formarea
de radicali liberi |
Structura
celulei este oxidata de actiunea agresiva a radicalilor
liberi |
 |
 |
-
Inalta concentratie de oxigen reactiv - radicalii liberi
si cantitatea insuficienta in organism de antioxidanti,
genera in organite (centrale energetice celulare) eficacitatea
scazuta a repararii ADN-ului, ca rezultat: Disfunctia
mitocondriala, care este o caracteristica a celulelor
maligne.
48 S-alilcisteina din Garlic un antioxidant previne stresul oxidativ si dauna renala
| Radicalii
liberi produc stres oxidativ |
Distrugerile
ADN-ului de radicalii liberi care produc stres
oxidativ |
 |
 |
- Mutatiile ADN-ului de
radicalii liberi afecteaza energia celulara ATP Administrarea
de antioxidanti ca factor anti cancer determina reversia
fenotipului malign prin inhibarea celulelor de cancer - Anti cancer: EGCG Galatul de epigalocatechina
| Degradarea
ADN-ului prin acumularea de 8-hidroxi-2’-deoxiguanozina |
Reversia
fenotipului malign prin inhibarea celulelor de
cancer |
 |
 |
Neutralizarea
de radicali liberi - Densitatea antioxidativa
Despre
antioxidanti: Antioxidantii sint molecule care apara
organismul de efectele oxigenului reactiv - Radicalii
liberi
Radicalii liberi produc stres oxidativ, iar antioxidantii apara celula
de radicalii liberi care sint molecule instabile, contin electroni neimperecheati,
adica un electron ocupa un singur orbital.
49 S-allilcisteina din Garlic un antioxidant amelioreaza neurotoxicitatea indusa
de acidul chinolinic si dauna oxidativa
Disfunctia
mitocondriala care este o caracteristica a celulelor
maligne, datorat prin capacitatea scazuta antioxidativa.
-
Antioxidanti se gasesc in orice celula, protejeaza organismul
de distrugerile provocate la nivel celular de radicalii
liberi.
- Antioxidantii pot neutraliza radicalii liberi limitind distrugerea provocata,
daca suficienti antioxidanti sint involvati - Capacitate suficienta antioxidativa
- Acid Alfa Lipoic prin proprietati si functie regenereaza alti antioxidanti
ca: Vitamina C, Vitamina E, Glutation, Coenzima Q10 ofera protectie antioxidativa
de efectele radicalilor liberi.
Antioxidantii
protejind celula de radicalii liberi - Capacitate suficienta

Sint o multime de antioxidanti
in extracte de plante naturale, fitofarmaceutice, nutraceutice
cu capacite de neutralizare a radicalilor liberi Antioxidanti
cheie: Acid Alfa Lipoic, Coenzima Q10, Vitamine: Vitamina
C, Vitamina E, Caretenoizi, (beta caroten,alfa caroten,
licopen, luteina, zeaxantina) Compusi fenolici: Flavonoizi,
polifenoli care confera protectie ridicata antoxidativa
- Suficienti
antioxidanti de recomandat: Acid Alfa Lipoic, Ceai Verde
EGCG, Vitamina C, Glutation, Vitamin E, Carotenoizi, Coenzima Q10 sau enzime antioxidante ca superoxid dismutaza (SOD) care detoxifica radicalul superoxid,
peroxidul de hidrogen (H 2O2) si Glutation peroxidaza (GPx) care detoxifica peroxizii celulari
- Spirulina contine
superoxid dismutaza (SOD) un antioxidant puternic 110000
Unitati/100g
Suficienti
antioxidanti de recomandat: Acid alfa lipoic, Ceai Verde, Vitamina C, Glutation, Vitamin E, Carotenoizi, Coenzima Q10 sau enzime antioxidante ca superoxid dismutaza (SOD) care detoxifica radicalul superoxid,
peroxidul de hidrogen (H2O2) si Glutation peroxidaza (GPx) care detoxifica peroxizii celulari
Antioxidantii protejind
celula de radicalii liberi - Capacitate suficienta

50 Efecte benefice ale Usturoiului si componenti sai principali activi: S-allilcisteina, S-alilmercaptocisteina, N(alfa)-fructosil
arginina
| Bibliografie-Referinte: |
 |
| Informatii din bibliografia electronica la tema: Nutritie si
sanatate |
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50 Amagase
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4 (Abstract)
Parerea din pasajele acestui site nu a fost independent cercetate
sau confirmate.
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