45 46 - Glicozilare sint reactii necontrolate ne-enzimatice ale glucozei cu proteinele Carnosina inhiba reactiile de glicozilare (AGEs), de brunificare si reducere a eslasticitatii tesutului de colagen in procesul de imbatrinire
47 48
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Bibliografie-Referinte: Beta Alanina

Informatii din bibliografia electronica la tema: Nutritie si sanatate
1. Harris RC, Ponte J, Sale C, Jones GA, Kim HJ, Wise JA. Effect of 14
and 28 days B-Alanine(Carnosyn™) supplementation on isometric endurance
of the knee extensors.Univeristy of Chichester, Chichester UK; Korea National
Sport Univeristy, Seoul Korea. Poster Presentation
2. Harris RC, Tallon MJ, Dunnett M, Hill C, Boobis L, Coakley J, Fallowfield
J, Kim HJ, Wise JA. The absorption of ß-Alanine into blood and its
effect on muscle carnosine synthesis in human vastus lateralis. In Press.
Amino Acids (2006).
3. Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA
(2006) Influence of b- alanine supplementation on skeletal muscle carnosine
concentrations and high intensity cycling capacity Amino Acids.
4. Harris RC, Hill CA, Boobis L, Tallon MJ and Wise JA. Elevation
of muscle carnosine content with administration of beta-alanine in the free
or peptide bound form. Experimental Biology, San Diego, April 2003.
- Harris RC, Dunnett M, Fallowfield J, Hesslink RL, Wise JA. Changes in plasma ß-alanine
concentration following administration of free or peptide bound forms. Experimental
Biology, San Diego, April 2003.
5. Derave W, Ozdemir MS, Harris RC, Pottier A, Reyngoudt H, Koppo K, Wise
JA, Achten E. beta-Alanine
supplementation augments muscle carnosine content and attenuates fatigue
during repeated isokinetic contraction bouts in trained sprinters. Dept.
of Movement and Sport Sciences, Ghent Univ., Watersportlaan 2, B-9000 Ghent,
Belgium. J Appl Physiol. 2007 Nov;103(5):1736-43. Epub 2007 Aug 9
6. Aonuma S, Hama T, Tamaki N, Okumura H. Orotate
as a beta-alanine donor for anserine and carnosine biosynthesis, and effects
of actinomycin D and azauracil on their pathway. J Biochem (Tokyo). 1969
Aug;66(2):123-32.
7. Fausto N. The conversion of orotic acid into uridine
5-monophosphate b y isolated perfused normal and regenerating rat livers.
Biochem.J. (1972) 129: 811-820.
8. Pels Rijcken WR, Hooghwinkle GJM, Ferwerda W. Pyrimidine
metabolism and sugar nucleotide synthesis in rat liver. Biochem J. 1990 March
15; 266(3): 777–783.
9. Yamamoto T, Moriwaki Y, Takahashi S, Tsutsumi Z, Yamakita J, Higashino
K. Effect
of muscular exercise on the concentration of uridine and purine bases in
plasma--adenosine
triphosphate consumption-induced pyrimidine degradation. Third Department
of
Internal
Medicine, Hyogo College of Medicine, Japan. Metabolism. 1997 Nov;46(11):1339-42.
10. Vianna Jorge, R : Oliveira, C F : Mounier, Y : Suarez Kurtz,
G Functional effects of uridine triphosphate on human skinned skeletal muscle
fibers. : Can-J-Physiol-Pharmacol. 1998 Feb; 76(2): 110-7
11. Kypson J, Hait G, Mathew R. (1978) Effects of uridine on the performance
and the metabolism of oxygenated and hypoxic rabbit hearts. J Mol Cell Cardiol.
10: 545-565.
12. Munsch CM, Williams JF, Conyers RAJ, O'Halloron K, Langley LH, Rosenfeldt
FL. The effect of orotic acid and ribose on the impaired tolerance of the
recently infracted rat heart to cardioplegic arrest. In: Williams JF, ed.
Orotic acid in cardiology. New York: Thieme Medical, 1992; 46-58.
13. Kreider RB, Melton C, Greenwood M, Rasmussen C, Lundberg J, Earnest C, Almada
A. Effects
of oral D-ribose supplementation on anaerobic capacity and selected metabolic
markers in healthy males. Exercise and Sport Nutrition Laboratory, Center
for Exercise, Nutrition and Preventative Health, in the Department of Health,
Human Performance and Recreation at Baylor University, Waco, TX 76798-7313, USA.
Int J Sport Nutr Exerc
Metab. 2003 Mar;13(1):76-86.
14. Richards SM, Conyers RA, Fisher JL, Rosenfeldt FL. Cardioprotection
by orotic acid: metabolism and mechanism of action. Baker Medical Research
Institute, Prahran, Victoria, Australia. J Mol Cell Cardiol. 1997 Dec;29(12):3239-50.00
- Rosenfeldt FL, Richards SM, Lin Z, Pepe S, Conyers RAJ. (1998) Mechanism of
cardioprotective effect of orotic acid. Cardio.Drug.Ther. 12: 159-170.
15. P. FERNINANDYa, f1, T. FAZEKASb, É. KÁDáÁR
Efects of orotic acid on ischemic repefused myocardial function and glycogen
content
in isolated working rat hearts Pharmacological Research Volume 37, Issue
2, February
1998, Pages 111-114
16. Williams JF, Donohoe J, Lykke A, Kolos G. (1976) Studies using orotic
acid for improving the controlled development of myocardial hypertrophy.
Aust.NZ.J.Med.
6 (Suppl.2): 60-71.
17. Geiss KR, Stergiou N, Jester , Neuenfeld HU, Jester HG. Effects
of magnesium orotate on exercise tolerance in patients with coronary heart disease. ISME
(Private
Research Institute for Sports, Medicine & Nutrition), Moerfelden, Germany.
Cardiovasc Drugs Ther. 1998 Sep;12 Suppl 2:153-6.
18. Golf SW, Bender S, Gruttner. (1998) On the significance of magnesium
in extreme physical stress. Cardio.Drug.Ther. 12: 197-202.
19. Gold SW. Is magnesium a limiting factor in competitive exercise A summary
of relevant scientific data. In: Gold SW, Dralle D, Vecchiet L. ed. Magnesium
1993. London: John Libbey, 1994: 209-219.
20. Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA.
Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations
and
high intensity cycling capacity. School
of Sports, Exercise & Health Sciences, University of Chichester, Chichester,
UK. Amino Acids. 2007 Feb;32(2):225-33. Epub 2006 Jul 28.
21
Stout JR, Cramer JT, Zoeller RF, Torok D, Costa P, Hoffman JR, Harris RC,
O'Kroy
J. Effects
of beta-alanine supplementation on the onset of neuromuscular fatigue and ventilatory
threshold in women. Department of Health and Exercise Science, University
of Oklahoma, Norman, OK 73019-6081, USA. Amino Acids. 2007;32(3):381-6. Epub
2006 Nov 30.
22
Zoeller RF, Stout JR, O'kroy JA, Torok DJ, Mielke M. Effects
of 28 days of beta-alanine and creatine monohydrate supplementation on aerobic
power, ventilatory and lactate
thresholds, and time to exhaustion. Department of Exercise Science and Health
Promotion, Florida Atlantic University, Davie, FL, U.S.A.. Amino Acids. 2007
Sep;33(3):505-10. Epub 2006 Sep 5.
23. Harris RC, Hill CA, Kim HJ, Boobis L, Sale C, Harris DB, Wise JA. Beta-alanine
supplementation for 10 weeks significantly increased muscle carnosine levels.
Experimental Biology, San Diego, April 2005.
24. Kim HJ, Kim CK, Lee YW, Harris RC, Sale C, Harris DB, and Wise JA (2006)
The effect of a supplement containing ß-alanine on muscle carnosine
synthesis and exercise capacity, during 12 wk combined endurance and weight
training. J. Inter. Soc. Sports Nutr. 3(1): S9
25
Hill CA, Harris RC, Kim HJ, Boobis L, Sale C, Wise JA. The effect
of beta-alanine and creatine monohydrate supplementation on muscle composition
and exercise performance. Medicine & Science in Sports and Exercise,
37(5), Supplement, S348, June 2005
26. Hoffman J, Stout JR, et al. Effect of creatine and ß-Alanine supplementation
on performance and endocrine responses in strength/power athletes. In Press.
International Journal of Sports Nutrition and Exercise Metabolism (2006).
27. Harris RC, Kim, CK, Kim HJ, Sale C, Wise JA. The effect
of a ß-alanine supplement on the muscle carnosine content during training.
9th International Congress on Amino Acids & Proteins, Vienna, August
2005.
28. Harris RC, Harris DB, Kim HJ, Hill CA, Boobis L, Sale C, Wise JA. The
distribution of carnosine in different muscle fibre types with beta-alanine
supplementation. Experimental Biology, San Diego, April 2005.
29
Stout JR, Cramer JT, Mielke M, O'Kroy J, Torok D, and Zoeller RF (2006)
Effects of 28 days of beta-alanine and creatine monohydrate supplementation
on the physical working capacity at neuromuscular fatigue threshold J Strength
Cond Res
31. Harris RC. Muscle carnosine elevation with supplementation and training,
and the effects of elevation on exercise performance. 2nd Annual International
Society of Sports Nutrition Conference, New Orleans, June 2005.
30. Kim HJ, Cho J. Kim CK, Harris RC, Harris RC, Sale C, Wise JA. Effect
of 12 days training of Korean speed skaters on muscle fibre morphology and
carnosine content. Medicine & Science in Sports and Exercise, 37(5) Supplement,
S192, June 2005.
32. Tallon MJ, Harris RC, Boobis L, Almada A, Wise JA, Murray
D. The effect of L-carnosine supplementation on its content in muscle and
types I & II muscle fibres. Experimental Biology, San Diego, April 2005.
33. Tallon MJ, Harris RC, Boobis L, Fallowfield J, Wise
JA. The carnosine content of vastus lateralis is elevated in resistance trained
bodybuilders. Journal of Strength & Conditioning Research, 19: 725-729,
2005.
34
Stuerenburg HJ. The roles of carnosine in aging of skeletal muscle and
in neuromuscular diseases. Biochemistry (Mosc). 2000 Jul;65(7):862-5.
35. Suzuki Y, Ito O, Mukai N, Takahashi H, Takamatsu K. High level of skeletal
muscle carnosine contributes to the latter half of exercise performance during
30-s maximal cycle ergometer sprinting. Doctoral Program in Health and Sport
Sciences, University of Tsukuba, Japan. Jpn J Physiol. 2002 Apr;52(2):199-205.
36. Tameyasu T, Yamada M, Tanaka M, Takahashi S. Effect of zinc-carnosine chelate
compound on muscle function in mdx mouse. Department of Physiology, St. Marianna
University School of Medicine, Kawasaki, 216-8511 Japan. t2tame@marianna-u.ac.jp.
Jpn J Physiol. 2002 Feb;52(1):111-20.
37
Rubtsov AM. Molecular mechanisms of regulation of the activity
of sarcoplasmic reticulum Ca-release channels (ryanodine receptors), muscle
fatigue, and Severin's phenomenon. Department of Biochemistry, School of
Biology, Lomonosov Moscow State University, Moscow, 119899, Russia.
Biochemistry (Mosc). 2001 Oct;66(10):1132-43.
38. Bulik, C. 1993. How the Spirulina, a green-blue
alga, preserves de cell from degeneration, and extends
youth and human lifespan. In: Doumenge, F., Durand-Chastel, H., Toulemont,
A., Eds. Spiruline algue de vie.
39
Hipkiss AR, Preston JE, Himsworth DT, Worthington VC, Keown M, Michaelis
J, Lawrence J, Mateen A, Allende L, Eagles PA, Abbott NJ. Pluripotent protective
effects of carnosine, a naturally occurring dipeptide. Molecular Biology
and Biophysics Group, King's College London, Strand, United Kingdom. Ann
N Y Acad Sci. 1998 Nov 20;854:37-53.
- Boldyrev AA, Gallant SC, Sukhich GT. Carnosine, the protective, anti-aging
peptide. Center for Molecular Medicine, Department of Biochemistry, Biological
Faculty, MV Lomonosov, Moscow State University, Vorobjovy Gory, Russia. Biosci
Rep. 1999 Dec;19(6):581-7.
Hipkiss AR, Brownson C. A possible new role for the anti-ageing peptide carnosine.Biomolecular
Sciences Division, GKT School of Biomedical Sciences, King's College London,
UK. Cell Mol Life Sci. 2000 May;57(5):747-53.
40
Hipkiss
AR. Glycation, ageing and carnosine: are carnivorous diets beneficial Centre
for Experimental Therapeutics, William Harvey Research Institute,
John Vane Science Centre, Bart's and the London Queen Mary's School of Medicine
and Dentistry, Charterhouse Square, London EC1M 6BQ, UK. Mech Ageing Dev.
2005 Oct;126(10):1034-9.
41
Hipkiss
AR. Would carnosine or a carnivorous diet help suppress aging and associated
pathologies Centre for Experimental Therapeutics, William
Harvey
Research Institute, Barts' and the London School of Medicine and Dentistry,
UK. Ann N Y Acad Sci. 2006 May;1067:369-74.
42
Hipkiss AR, Brownson C, Carrier MJ. Carnosine, the anti-ageing, anti-oxidant
dipeptide, may react with protein carbonyl groups. Division of Biomolecular
Sciences, GKT School of Biomedical Sciences, King's College London, Guy's
Campus,
London
Bridge, London SE1 1UL, UK.
Mech Ageing Dev. 2001 Sep 15;122(13):1431-45.
43
Hipkiss AR. Carnosine and protein carbonyl groups: a possible relationship.
Division of Biomolecular Sciences, GKT School of Biomedical Sciences, King's
College London, London SE1 1UL, UK. Biochemistry (Mosc). 2000 Jul;65(7):771-8.
44
Gariballa SE, Sinclair AJ. Carnosine: physiological properties and therapeutic
potential. Sheffield Institute of Studies on Ageing, The University of Sheffield,
Barnsley General Hospital, UK.
Age Ageing. 2000 May;29(3):207-10.
45
Hipkiss AR, Michaelis J, Syrris P. Non-enzymatic glycosylation of the dipeptide
L-carnosine, a potential anti-protein-cross-linking agent. FEBS Lett. 1995; 371(1):81-5.
- Burcham PC, Kuhan YT. Diminished susceptibility to proteolysis after protein
modification by the lipid peroxidation product malondialdehyde: inhibitory role
for crosslinked and noncrosslinked adducted proteins. Arch Biochem Biophys. 1997;
340(2):331-7.
- Brownson C, Hipkiss AR. Carnosine reacts with a glycated protein. Division
of Biomolecular Science, GKT School of Biomedical Sciences, King's College London,
Guy's Campus, London Bridge, London,
UK. Free Radic Biol Med. 2000 May 15;28(10):1564-70.
Hipkiss AR, Preston JE, Himswoth DT, Worthington VC, Abbot NJ. Protective effects
of carnosine against malondialdehyde-induced toxicity towards cultured rat brain
endothelial cells. Molecular Biology and Biophysics Group, King's College London,
Strand, UK. Neurosci Lett. 1997 Dec 5;238(3):135-8.
- Hipkiss AR, Worthington VC, Himsworth DT, Herwig W. Protective effects of carnosine
against protein modification mediated by malondialdehyde and hypochlorite. Molecular
Biology and Biophysics Group, King's College London, UK. Biochim Biophys Acta.
1998 Mar 12;1380(1):46-54.
- Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP. AGEs and their interaction with
AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept.
Department of Medicine I, University of Heidelberg, Germany. Cardiovasc Res.
1998 Mar;37(3):586-600.
46
Burcham PC, Kuhan YT. Diminished susceptibility to proteolysis after
protein modification by the lipid peroxidation product malondialdehyde: inhibitory
role for crosslinked and noncrosslinked adducted proteins. Arch Biochem Biophys.
1997; 340(2):331-7.
- Brownson C, Hipkiss AR. Carnosine reacts with a glycated protein. Division
of Biomolecular Science, GKT School of Biomedical Sciences, King's College
London, Guy's Campus, London Bridge, London, UK. Free Radic Biol Med. 2000
May 15;28(10):1564-70.
- Hipkiss AR, Michaelis J, Syrris P. Non-enzymatic glycosylation of the dipeptide
L-carnosine, a potential anti-protein-cross-linking
agent. FEBS Lett. 1995; 371(1):81-5.
Hipkiss AR, Preston JE, Himswoth DT, Worthington VC, Abbot NJ. Protective effects
of carnosine against malondialdehyde-induced toxicity towards cultured rat brain
endothelial cells. Molecular Biology and Biophysics Group, King's College London,
Strand, UK. Neurosci Lett. 1997 Dec 5;238(3):135-8.
- Hipkiss AR, Worthington VC, Himsworth DT, Herwig W. Protective effects of carnosine
against protein modification mediated by malondialdehyde and hypochlorite. Molecular
Biology and Biophysics Group, King's College London, UK. Biochim Biophys Acta.
1998 Mar 12;1380(1):46-54.
- Bierhaus A, Hofmann MA, Ziegler R, Nawroth PP. AGEs and their interaction with
AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept.
Department of Medicine I, University of Heidelberg, Germany. Cardiovasc Res.
1998 Mar;37(3):586-600.
47
Hipkiss AR, Chana H. Carnosine protects proteins against methylglyoxal-mediated
modifications. Molecular Biology and Biophysics Group, King's College London,
United Kingdom. Biochem Biophys Res Commun. 1998 Jul 9;248(1):28-32.
48
Thorpe SR, Baynes JW. Role of the Maillard reaction in diabetes mellitus
and diseases of aging. Department of Chemistry and Biochemistry, University
of South Carolina, Columbia 29208, USA. Drugs Aging. 1996 Aug;9(2):69-77.
- David L. Price, Patricia M. Rhett, Suzanne R. Thorpe, and John W. BaynesDagger.
Chelating Activity of Advanced Glycation End-product Inhibitors. From the
Department of Chemistry and Biochemistry, University of South Carolina, Columbia,
South Carolina 29208. J. Biol. Chem., Vol. 276, Issue 52, 48967-48972, December
28,
2001
49
Babizhayev MA, Seguin MC, Gueyne J, Evstigneeva RP, Ageyeva EA, Zheltukhina
GA. L-carnosine (beta-alanyl-L-histidine) and carcinine (beta-alanylhistamine)
act as natural antioxidants with hydroxyl-radical-scavenging and lipid-peroxidase
activities. Moscow Helmholtz Research Institute of Eye Diseases, Russia.
Biochem J. 1994 Dec 1;304
( Pt 2):509-16.
- Decker EA, Livisay SA, Zhou S. A re-evaluation of the antioxidant activity
of purified carnosine. Department of Food Science, Chenoweth Lab, University
of Massachusetts, Amherst, MA 01003, USA. edecker@foodsci.umass.edu. Biochemistry
(Mosc). 2000 Jul;65(7):766-70.
- Chan WK, Decker EA, Chow CK, Boissonneault GA. Effect of dietary carnosine
on plasma and tissue antioxidant concentrations and on lipid oxidation in rat
skeletal muscle. Department of Animal Sciences, University of Massachusetts,
Amherst 01003. Lipids. 1994 Jul;29(7):461-6.
- Hartman PE, Hartman Z, Ault KT. Scavenging of singlet molecular
oxygen by imidazole compounds: high and sustained activities of carboxy terminal
histidine dipeptides and exceptional activity of imidazole-4-acetic acid. Department
of Biology, Johns Hopkins University, Baltimore, MD 21218. Photochem Photobiol.
1990 Jan;51(1):59-66.
- Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Kondo M. The antioxidant
properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinato
zinc. First Department of Medicine, Kyoto Prefectural University of Medicine,
Japan. Biochim Biophys Acta. 1991 Nov 14;1115(1):15-22.
- Gulyaeva NV, Dupin AM, Levshina IP. Carnosine prevents activation of free-radical
lipid oxidation during stress. Bull Exp
Biol Med. 1989; 107(2):148-152.
- Gulyaeva NV. Superoxide-scavenging activity of carnosine in the presence of
copper and zinc ions. Biochemistry (Moscow). 1987; 52(7 Part 2):1051-4.
50. Chan WK, Decker EA, Chow CK, Boissonneault GA. Effect of dietary
carnosine on plasma and tissue antioxidant concentrations and on lipid oxidation
in rat skeletal muscle. Department of Animal Sciences, University of Massachusetts,
Amherst 01003. Lipids. 1994 Jul;29(7):461-6.
- Kang JH, Kim KS, Choi SY, Kwon HY, Won MH, Kang TC. Protection by carnosine-related
dipeptides against hydrogen peroxide-mediated ceruloplasmin modification. Department
of Genetic Engineering, Chongju University, Korea.
Mol Cells. 2002 Feb 28;13(1):107-12
51. Preston JE, Hipkiss AR, Himsworth DT, Romero IA, Abbott JN. Toxic effects
of beta-amyloid(25-35) on immortalised rat brain endothelial cell: protection
by carnosine, homocarnosine and beta-alanine. Institute of Gerontology, King's
College
London, UK. Neurosci Lett. 1998 Feb 13;242(2):105-8.
- Munch G, Schinzel R, Loske C, et al. Alzheimer's disease-synergistic effects
of glucose deficit, oxidative stress and advanced glycation endproducts. Journal
of Neural Transmission. 1998; 105(4-5):439-61
52. Horning MS, Blakemore LJ, Trombley PQ. Endogenous mechanisms of neuroprotection:
role of zinc, copper, and carnosine. Brain Res. 2000; 852(1):56-61.
- Stvolinsky SL, Kukley ML, Dobrota D, et al. Carnosine: an endogenous neuroprotector
in the ischemic brain. Cell Mol Neurobiol. 1999; 19(1):45-56.
- Boldyrev AA, Stvolinsky SL, Tyulina OV, et al. Biochemical and physiological
evidence that carnosine is an endogenous neuroprotector against free radicals.
Cell Mol Neurobiol. 1997; 17(2):259-71.
- Dukic-Stefanovic S, Schinzel R, Riederer P, Munch G. AGES in brain ageing:
AGE-inhibitors as neuroprotective and anti-dementia drugs Physiological Chemistry
I, Biocenter, University of Wurzburg, Germany. Biogerontology. 2001;2(1):19-34.
53. Gallant S, Semyonova M, Yuneva M. Carnosine as a potential anti-senescence
drug. Zoetic Neurosciences Ltd., Leighton Buzzard, Beds, LU7 7NW, Great
Britain. Biochemistry (Mosc). 2000 Jul;65(7):866-8.
Literatura:
Dr. Ronald Klatz, MD. Robert Goldman - Stopping the Clock: Dramatic Breakthroughs in Anti Aging and Aging Reversal Techniques
Dr. MD. Roy L Waldford - Beyond the 120 Year Diet: How to Double Your Vital Years
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